BDBM188335 US9670203, Compound 1.41
SMILES Fc1ccc(NC(=O)N[C@@H]2[C@H]3Oc4ccc(Oc5ccnc6NC(=O)CCc56)cc4[C@@H]23)cc1
InChI Key InChIKey=SVJXCDPMCSOTJX-FKBYEOEOSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 188335
TargetRAF proto-oncogene serine/threonine-protein kinase [306-648,Y340D,Y341D](Homo sapiens (Human))
Beigene
US Patent
Beigene
US Patent
Affinity DataIC50: 150nMT: 2°CAssay Description:Compounds disclosed herein were tested against B-Raf (V600E) (PV3849, from Invitrogen) or C-Raf (Y340D/Y341D) (PV3805, from Invitrogen) in a time-res...More data for this Ligand-Target Pair